Introduction
Osteoarthritis (OA) is a prevalent degenerative joint disease characterized by cartilage degradation, subchondral bone changes, and synovial inflammation. Traditional treatments focus on symptom management, often overlooking the underlying degenerative processes. At RegenU, we employ regenerative therapies aimed at restoring joint integrity and function.
Understanding Osteoarthritis Pathophysiology
OA involves the progressive breakdown of articular cartilage, leading to joint pain, stiffness, and reduced mobility. Contributing factors include mechanical stress, biochemical changes, and inflammatory mediators that disrupt the balance between cartilage synthesis and degradation.
Regenerative Therapies in OA Management
Platelet-Rich Plasma (PRP)
PRP therapy utilizes autologous blood concentrates rich in growth factors to promote cartilage repair and modulate inflammation. Clinical studies have demonstrated PRP’s efficacy in reducing OA symptoms and improving joint function (Foster et al., 2009).
Hyperbaric Oxygen Therapy (HBOT)
HBOT involves breathing pure oxygen in a pressurized environment, increasing oxygen delivery to hypoxic joint tissues. This therapy has been associated with reduced inflammation and enhanced chondrocyte activity, contributing to cartilage preservation (Slater et al., 2022).
Conclusion
Regenerative therapies offer a multifaceted approach to OA management, targeting the disease’s root causes rather than merely alleviating symptoms. By integrating PRP, MSCs, and HBOT into treatment protocols, RegenU aims to restore joint health and improve patient quality of life.
Disclaimer: This blog is for informational purposes only and should not be considered medical advice. Please consult with your healthcare provider for any questions or concerns regarding your health.
References
- Foster, T. E., Puskas, B. L., Mandelbaum, B. R., Gerhardt, M. B., & Rodeo, S. A. (2009). Platelet-rich plasma: from basic science to clinical applications. The American Journal of Sports Medicine, 37(11), 2259–2272. https://doi.org/10.1177/0363546509349921
- Slater, G., Malley, M. O., Slater, T., & Sambo, T. (2022). Hyperbaric Oxygen Therapy: An Overview. Journal of Regenerative Biology and Medicine, 4(3), 1–15. https://doi.org/10.37191/Mapsci-2582-385X-4(3)-111