April marks Autism Awareness Month, a time to celebrate neurodiversity and spotlight advances in care that can enhance quality of life for individuals on the autism spectrum disorder (ASD). One therapy gaining increased attention is
Hyperbaric Oxygen Therapy (HBOT)—a non-invasive treatment that may offer supportive benefits to individuals with autism by targeting some of the underlying physiological imbalances often observed in the condition.
At RegenU, we recognize that while autism is not something that needs to be “cured,” individuals with ASD often face real challenges related to inflammation, oxidative stress, and neurodevelopment. HBOT has shown promise in helping to address these physiological components, improving the lived experience of children and adults with autism.
Understanding HBOT and Its Mechanism
HBOT involves breathing 100% oxygen in a pressurized chamber, significantly increasing the amount of oxygen delivered to tissues throughout the body—including the brain. This oxygen saturation has been shown to reduce inflammation, promote healing, and stimulate neurological activity in a number of conditions.
In the context of autism, HBOT is thought to:
- Reduce oxidative stress and inflammation (Rossignol et al., 2009)
- Improve mitochondrial function and cellular metabolism (Stoller, 2017)
- Enhance cerebral perfusion and blood flow in areas often underactive in ASD brains (Rossignol et al., 2009)
While HBOT is not a standalone treatment or a replacement for behavioural or educational interventions, it may serve as a supportive therapy in a comprehensive autism care plan.
Clinical Insights: What the Research Says
A landmark randomized, double-blind, controlled trial published in BMC Paediatrics found significant improvements in autistic children undergoing 40 sessions of HBOT at 1.3 ATM with 24% oxygen. Improvements included better language skills, social interaction, eye contact, and sensory awareness (Rossignol et al., 2009). These children also showed reductions in markers of inflammation and oxidative stress—two physiological processes frequently elevated in autism.
These findings are consistent with what we understand from Dr. Gordon Slater’s broader work in regenerative and vascular medicine: improved oxygen delivery enhances the body’s natural healing processes (Slater, n.d.). While Dr. Slater’s primary focus is orthopaedic and vascular conditions, the same principles of inflammation modulation and enhanced cellular metabolism apply to neurological and developmental health.
Parents and Practitioners: What to Know
At RegenU, families who have trialled HBOT for children with ASD often report:
- Better regulation of mood and behaviour
- Reduced irritability and tantrums
- Improvements in sleep quality and digestive health
- More sustained attention and cognitive engagement
HBOT is safe when administered under medical supervision. It’s important that families work closely with healthcare professionals who understand both autism and HBOT to tailor the therapy appropriately.
Conclusion: Progress, Not Perfection
Autism is a spectrum, and so is progress. HBOT is not a cure, but it may provide real relief and support for some individuals on the autism spectrum—especially when used as part of a personalized and integrative care plan.
As we deepen our understanding of the biological factors contributing to autism, therapies like HBOT shine a light on new possibilities. At RegenU, we’re proud to offer evidence-informed options that honour both science and individuality.
Disclaimer: This blog is for informational purposes only and should not be considered medical advice. Please consult with your healthcare provider for any questions or concerns regarding your individual health.
Reference List
- Rossignol, D. A., Rossignol, L. W., Smith, S., Schneider, C., Logerquist, S., Usman, A., … & Bradstreet, J. J. (2009). Hyperbaric treatment for children with autism: a multicenter, randomized, double-blind, controlled trial. BMC Pediatrics, 9, 21. https://bmcpediatr.biomedcentral.com/articles/10.1186/1471-2431-9-21
- Slater, G. (n.d.). Enhancing surgical recovery with hyperbaric oxygen therapy. Orthopaedic Surgeon Australia. Retrieved from https://orthopaedic-surgeon.com.au/enhancing-surgical-recovery-with-hyperbaric-oxygen-therapy-hbot/
- Stoller, K. P. (2017). Hyperbaric oxygen therapy (HBOT) as a brain repair tool. Medical Gas Research, 7(4), 214–219. https://doi.org/10.4103/2045-9912.219246